奧美拉唑
別稱: 洛塞克;歐麥亞砜;亞砜米唑;左旋奧美拉唑;艾美拉唑
英文名稱: Omeprazole
CAS號(hào): 73590-58-6
分子式: C17H19N3O3S
分子量: 345.42
熔點(diǎn): 156°C
沸點(diǎn): 600.0±60.0 °C(Predicted)
密度: 1.332 g/cm3
儲(chǔ)存條件: 2-8°C
溶解度在水中的溶解度: 0.5 mg/mL
形態(tài): 固體
穩(wěn)定性: 穩(wěn)定，但有吸濕性和光敏性。與強(qiáng)氧化劑不相容。避光保存。
結(jié)構(gòu)式:
化學(xué)性質(zhì): 從乙腈結(jié)晶，熔點(diǎn)156℃。
用途: 奧美拉唑是一種質(zhì)子泵抑制劑，對(duì)動(dòng)物和人胃酸分泌具有很強(qiáng)的和較長(zhǎng)時(shí)間的抑制作用。
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A by UV |
Ratio of absorbance is 1.6 to 1.8 |
1.7 |
|
B by IR |
IR Conforms to the standard |
Positive |
|
C by TLC |
Conforms to the standard |
Positive |
|
Appearance of solution |
Solution should be clear |
Solution is clear |
|
Absorbance |
At 440nm is not more than 0.1 |
0.02 |
|
Impurity C |
BY TLC, not more intense than 0.1% |
＜0.1% |
|
Related substances by HPLC |
|
|
|
Any individual impurity |
Not more than 0.1% |
＜0.1% |
|
Residual solvent |
|
|
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Acetone |
Not more than 5000ppm |
Below detection limit |
|
Methanol |
Not more than 3000ppm |
Below detection limit |
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Dichloromethane |
Not more than 100ppm |
Below detection limit |
|
Acetonitrile |
Not more than 410ppm |
Below detection limit |
